The machine is suitable for injection or penicillin bottle in the blister tray box, injection In finishing blister, similar blister package product, adjust automatic feeding structure conveniently, setup quantity of blisters on touch screen randomly. On line product feeding and detecting, leaflet fold(1-4folds) and feeding, leaflet detecting, canton opening and forming, products and leaflet pushing into carton, printing batch number, sealing carton with tuck-in or hot melt glue device. Automatically reject lacking of leaflet or product and finished product out.